Curriculum Vitae






Postdoctoral Fellowship

Vanderbilt University Medical Center

Focus: Neuropharmacology

Completed: 2015


Doctor of Philosophy

University of Florida

Major: Entomology (Neurotoxicology)

Degree Earned: 2012


Master of Science

Virginia Tech

Major: Life Sciences (Entomology)

Degree Earned: 2009


Bachelor of Science

Christopher Newport University

Major: Biology and Chemistry

Degree Earned: 2008



Selected Refereed Publications


1. Daniel R. Swale, Emily Days, Paige Vinson, Matt Rouhier, Peter M. Piermarini, Corey Hopkins, Jerod S. Denton.  Development of the first topically active insecticide targeting inwardly rectifying potassium channels.  Manuscript submitted to PNAS: December 2015


2. Jennifer L Herington, Daniel R. Swale, Naoko Brown, Elaine Shelton, Charles H. Williams, Charles C. Hong, Bibhash C. Paria, Jerod S. Denton, Jeff Reese.  High-Throughput screening of myometrial calcium-mobilization to identify modulators of uterine contractility.  PLoS ONE, 10(11): e0143243. doi:10.1371/journal.pone.0143243


3. James M. Mutunga, Troy D. Anderson, Derek T. Craft, Aaron D. Gross, Daniel R. Swale, Fan Tong, Dawn M. Wong, Paul R. Carlier, and Jeffrey R. Bloomquist. 2015. Carbamate and Pyrethroid Resistance in the Akron Strain of Anopheles gambiae.  Pesticide Biochemistry and Physiology. Special Issue: IUPAC proceedings honoring Ralf Nauen. 121: 116-121


4. Daniel R. Swale, Jonathan H. Sheehan, Afeef S. Husni, Thuy Nguen, Jens Meiler, Jerod S. Denton.  2015.  Computational and functional analysis of the small-molecule binding site in ROMK. Biophysical Journal 108:1094-1103


5. Rene Raphemot, Matthew F Rouhier, Daniel R. Swale, Emily Days, C. David Weaver, Kimberly M Lovell, Leah C Konkel, Darren W Engers, Sean F Bollinger, Corey Hopkins, Peter M. Piermarini, Jerod S. Denton.  2014.  Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels. PLoS ONE 9(11):e110772. doi: 10.1371/journal.pone.0110772


6. Daniel R. Swale, Paul R. Carlier, Joshua A. Hartsel, Ming Ma, Jeffrey R. Bloomquist.  Mosquitocidal carbamates with low toxicity to agricultural pests: An advantageous property for insecticide resistance management.  In Press (September 2014):  Pest Management Science


7. Daniel R. Swale, Baonan Sun, Fan Tong, Jeffrey R. Bloomquist. 2014.  Neurotoxicity and mode of action of N,N-diethyl-meta-toluamide (DEET). PLoS ONE 9(8): e103713. doi:10.1371/journal.pone.0103713


8. Rene Raphemot, Daniel R. Swale, Prasanna K. Dadi, David A. Jacobson, Paige Cooper, Andrew P. Wojtovich, Sreedatta Banerjee, Colin Nichols, Jerod S Denton.  2014.  Direct activation of beta-cell KATP channels with a novel xanthine derivative. Molecular Pharmacology. doi:10.1124/mol.114.091884


9. Daniel R. Swale, Fan Tong, Kevin Temeyer, Andrew Li, Polo Lam, Maxim Totrov, Paul Carlier, Aldaberto Perez de Leon, Jeffrey Bloomquist.  2013.  Inhibitor profile of bis(n)-tacrines and N-methylcarbamates on acetylcholinesterase from Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi.    Pesticide Biochemistry and Physiology 106: 85-92


10. Ying Jiang, Daniel R. Swale, Paul R. Carlier, Joshua A Hartsel, Ming Ma, Fredrik Ekstrom, Jeffrey Bloomquist.  2013.  Evaluation of Novel Carbamate Insecticides for Neurotoxicity to Non-Target Species.   Pesticide Biochemistry and Physiology 106: 156–161


11. Maia Tsikolia, Ulrich R. Bernier, Monique R Coy, Katelyn C. Chalaire, James J. Becnel, Natasha M, Agramonte, Nurhayat Tubanca, David E. Wedge, Gary G. Clark, Kenneth J. Linthicum, Daniel R. Swale, Jeffrey R. Bloomquist.  2013.  Insecticidal and Fungicidal Properties of Novel Trifluoromethylphenyl Amides.  Pesticide Biochemistry and Physiology 107: 138-147


12. Monique Mathe-Allainmat, Daniel R. Swale, Xavier Leray, Yassine Benzidane, Jacques Lebreton, Jeffrey R. Bloomquist, Steeve H. Thany.  2013. Quinuclidine compounds differently act as agonists of Kenyon cell nicotinic acetylcholine receptors and induced distinct effect on insect ganglionic depolarizations. Invertebrate Neuroscience. 13(2):167-77. DOI: 10.1007/s10158-013-0160-2



Invited Reviews

1. Sujay V. Kharade, Daniel R. Swale, Jerod S. Denton.  2015.  ROMK Pharmacology Comes of Age.  Channels.  Invited Commentary Based upon Swale et al., Biophysical Journal.  9(3): 119-120.  doi: 10.1080/19336950.2015.1046733


2. Daniel R. Swale, Sujay V. Kharade, Jerod S. Denton.  2014.  Cardiac and Renal Inward Rectifier Potassium Channel Pharmacology: Emerging Toolkit for Integrative Physiology and Therapeutics.  Current Opinions in Pharmacology.  15: 7-15




Selected Invited Presentations


1. Daniel R. Swale.  2016.  Novel approaches for malaria control: exploiting potassium ion channels and insect growth regulators in attract and kill strategies.  International Centre for Insect Physiology and Ecology.  Nairobi, Kenya.  Invited by Dr. James Mutunga


2. Daniel R Swale.  2015.  Inwardly rectifying potassium channels: An underexplored but critical physiological target site.  Louisiana Mosquito Control Association. Lake Charles, LA, USA.


3. Daniel R Swale.  2015. Neural Kir Channels: A critical conductance pathway in insect nervous systems.  Society of Vector Ecology (SOVE).  Albuquerque, NM, USA


4. Daniel R. Swale.  2015.  Characterizing the Physiological Influences of Inward Rectifying Potassium Channels in Insect Tissue Systems.  Kansas State University Seminar Series, Manhattan, KS.  Invited by:  Professor Yoonseong Park


5. Daniel R. Swale.  2015.  Physiological role of inwardly rectifying potassium channels in the insect nervous system. American Chemical Society Fall National Meeting: Agrochemical Division.  Boston, MA, USA


6. Daniel R. Swale, Peter M. Piermarini, Jerod S. Denton.  2014.  Development of novel mosquitocides targeting inwardly rectifying potassium channels in the malaria vector, Anopheles gambiae.  American Chemical Society, IUPAC, San Francisco, CA, USA


7. Daniel R. Swale.  2014.  Identification of novel inhibitors of inwardly rectifying potassium channels in human and mosquito.  Virginia Tech, Department of Entomology Seminar Series.  Blacksburg VA, USA. Invited by Dr. Troy Anderson


8. Daniel R. Swale.  2012.  Development of novel anticholinesterases for control of the malaria vector, Anopheles gambiae.  Center for Disease Control and Prevention, Entomology Branch.  Atlanta, GA, USA.


9. Jeffrey R. Bloomquist and Daniel R. Swale.  2012.  Neurotoxicology of N,N-diethyl-meta-toluamide (DEET).  American Chemical Society Fall National Meeting: Agrochemical Division, Integrated Vector and Resistance Management Symposium.  Philadelphia, PA, USA.